4th IRN iGPCR workshop 2024 Pharmacology in Drug Discovery

4^th IRN iGPCR workshop 2024

Pharmacology in Drug Discovery

Dear PhD students and postdoctoral researchers of the iGPCRnet IRN and attendees of the meeting,

Commencing on the day after the 4^th annual iGPCRnet meeting (11^th of July 2024), the workshop in Nottingham will be based on a well-established due diligence exercise where small teams of 4-5 will work through data provided by three companies on a promising drug candidate. The ultimate aim is for each group to make a recommendation to senior management for in-licencing of one selected candidate drug. The exercise will be preceded by two lectures giving the background to analysis of ligand-binding and functional responses of GPCRs.

Programme

09:00 - 09:30: Dr. Laura Kilpatrick – An introduction to Pharmacology in Drug Discovery

09:30 - 10:30: Prof. Steve Hill – Lecture 1: An Introduction to Ligand Binding

10:30 - 11:00: Coffee break

11:00 - 12:00: Prof. Steve Hill – Lecture 2: Measurement of Functional Responses

12:00 - 12:45: Lunch

12:45 - 13:00: Introduction to the Workshop

13:00 - 15:00: Workshop: Due Diligence Data Exercise and Hands-On Cellular Assays Provided by BMG Labtech and Promega

15:00 - 15:30: Workshop feedback

Registration: https://form.jotform.com/240855290408963

Practical information :

How to get to Nottingham:

By train (international):

Eurostar to London St. Pancras

Eurostar trains arrive in London St. Pancras. Direct trains to Nottingham leave from this station.

By air:

East midlands airport

Directly connected to Nottingham, via skylink bus 1 hour, leaves every 20 minutes.

25-minute drive by car/taxi.

Birmingham airport

Connected to Nottingham via train, connecting in Birmingham New Street. Journey time 2 hours.

London Luton airport

Directly connected to Nottingham via train, 1 hour 40 minutes.

Other London airports

When flying into other London airports such as Stansted, Gatwick, or Heathrow, change trains in London. Trains to Nottingham leave from London St. Pancras.

Total journey time 3-4 hours.

Getting around Nottingham:

Both buses and trams can be paid for using contactless debit/credit cards.

Trams:
The tram is the most efficient option to travel from Nottingham Train Station to the University.

Toton Lane tram line runs from the centre of Nottingham and Nottingham Train Station to the University Park tram stop which is the closest to the conference venue and the Queen’s Medical Centre (QMC).

Buses:

NCT bus routes 34, 35, and 36 run the centre of Nottingham to Queen’s Medical Centre and University Park.