PhD Position in GPCR Biochemistry & Biophysics in Pr G. Krainer lab at Graz University (Austria)
PhD Position in GPCR Biochemistry & Biophysics
The Molecular Biophysics Group, led by Prof. Georg Krainer at the Institute of Molecular Biosciences (IMB), University of Graz, Austria, is seeking a highly motivated and talented PhD candidate to join the ERC-funded project “SignAlloMod: Decoding the Molecular Logic of G Protein-Coupled Receptor (GPCR) Signaling”.
About the Position:
This role focuses on GPCR structure, dynamics, and interactions at the single-molecule level, combining biochemical, biophysical, and single-molecule approaches. Key tasks include:
- Expression & purification of GPCRs in insect/mammalian cells
- Reconstitution in nanodiscs/liposomes & functional characterization
- Development of single-molecule assays to study GPCR signaling mechanisms
Who Should Apply:
Candidates must have (or be near completion of) a Master’s degree in Biochemistry, Biophysics, Structural Biology, or a related field with expertise in:
- Protein biochemistry & purification of membrane proteins (preferably GPCRs), including protein expression in insect & mammalian systems (required)
- Experience in single-molecule methods and fluorescence spectroscopy is desirable
What We Offer:
- 4-year fixed-term contract (1 + 3 years, 75% FTE, approx. 39,000 € gross/year)
- State-of-the-art facilities for single-molecule research and protein biochemistry
- Collaborative research environment & career development opportunities
How to Apply:
Send a single PDF to georg.krainer@uni-graz.at, including:
- Cover letter (research interests & expertise)
- CV & publication list
- Contact info for 2–3 references
Applications are reviewed on a rolling basis until the position is filled.
Start Date: As soon as possible or upon mutual agreement.
Research Environment: The University of Graz is one of Austria’s largest academic institutions, fostering a collaborative and innovative research environment. Situated in the vibrant city of Graz, the Institute of Molecular Biosciences (IMB) provides cutting-edge infrastructure for interdisciplinary research at the interface of biophysics, biochemistry, and molecular biology. Our motto: We work for tomorrow.