K.N.

KEY NUMBERS and FACTS of the i-GPCRnet IRN

2021: year of creation of the IRN

5: number of years that the IRN has been approved by the CNRS

82: number of academic IRN member teams

65: number of French IRN teams

14: number of British IRN teams

2: number of German IRN teams

1: number of Chinese IRN teams

~600: number of academic IRN members

9: number of years of the existence of the GDR3545, the precursor of the IRN

~800: estimated number of GPCRs in humans

3: Number of Nobel Prizes on GPCR-related issues

30-40%: estimated % of currently marketed drugs targeting GPCRs

27%: GCPRs are the most lucrative drug targets with ~27% of the overall sales (period 2011-2015)

7: Number of drugs targeting GPCRs among the Top 20 drugs on the market (period 2011-2015)

17%: of GPCRs currently exploited as drug targets

~100: Number of orphan GPCRs